Best methods of infertility treatment:

Nowadays due to advances in medical sciences and various methods for infertility treatment, the joy of having a child is within the reach of almost anybody. Medical treatments along with assisted reproduction techniques has improved the chance for many men and women with infertility problems to have children. This article gives you useful information about prominent methods of infertility treatment.

The process of infertility treatment:

After various diagnostic tests, different methods of infertility treatment will be applied in accordance with the cause of infertility. After explaining each method and its success rate, doctor provides the couple with different treatment options to choose the one that suits them the most regarding their situation and preferences.

• In vitro fertilization or IVF:

IVF is a prevalent method to treat infertility problems and consisted of a complex series of procedures. During IVF, after stimulating ovaries and ovulation, mature eggs are retrieved from ovaries and fertilized by sperm outside the uterus in a lab. After the conception of embryo in the lab, the embryo is then placed inside the uterus.

This method is usually offered in conditions where sperm can’t reach the egg naturally, such as blocked fallopian tubes, pelvic adhesions, low sperm count or low sperm mobility.

• Intrauterine insemination IUIDuring intrauterine insemination IUI which is a simple and painless procedure to facilitate fertilization, the sperm is placed inside the uterus. For IUI to work(hazf) , the fallopian tubes need to be healthy. In this method the egg is not retrieved from ovaries and the process of ovulation and conception occurs naturally.
• Ovulation stimulation by advanced protocols:
• Ovulation stimulation is helpful for women with irregular ovulation, ovulation disorder or polycystic ovary (PCO) and mostly used to increase the quantity and quality of eggs and boost the chance of fertilization. There are medications that induce the same effect on egg quality and quantity which are known as ovulation induction medicine.
• Micro injection or intracytoplasmic sperm injection ICSI
• Micro injection is an infertility treatment method that a sperm cell is injected directly into the cytoplasm of an egg and cultivate it for a specific period of time in an incubator. After conception and cell division, embryo is made.
• In vitro maturation IVM:
• With IVM, instead of increasing follicle growth in body (metaphase 2), immature eggs are extracted from ovaries using a vaginal sonography. Afterwards, extracted eggs are grown in a laboratory and fertilized before being replaced into the womb.
• Gamete intrafallopian transfer GIFT:

• GIFT method is mostly used in cases of surrogate womb and is similar to IVF in terms of egg retrieving and sperm preparation. Afterwards, the egg along with adequate amount of sperm are placed directly into the fallopian tubes using a laparoscope.

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IVF: success rate

What is IVF success rate in Iran?

IVF success rate is an important point you should notice before performing IVF.

IVF is an infertility treatment technique for infertile couples with appropriate and high success rate in Iran compared to other countries.

 

What is IVF success rate in Iran compared to other countries?

Fortunately, Iran has a lot of experience in infertility treatment science with high IVF success rate compared to countries all over the world and many patients travel to Iran to treat their infertility problems every year.

To evaluate IVF success rate, patients are divided into 2 groups: women age less than 35 years old and women age more than 35 years old.

The success rate of IVF in first group (women <35 y/o) is approximately 40 % and the success rate of IVF in second group (women > 35 y/o) is 15- 20% on average.

IVF success rate differs in fertility clinics and centers depend on many factors.

IVF success rate in Iran is equal or more than global statistics.

IVF in Iran has affordable costs which make Iran an attractive destination for infertility treatment and medical travelers.

High medical care experiences along with fair prices highlight Iran as a leading destination for infertility treatment all over the world.

What affects IVF success rate?

IVF is a technique to treat infertility problems such as sperm count, shape or motility problems or insufficient egg production.

IVF is done in special laboratory environment and many factors affect IVF success rate which mentioned as below:

 

 

Age:

First and most important factor affecting the success rate of IVF is age. The older you get, the lower your chance of successful IVF. In younger 

IVF : Infertility treatment:

 

as medical science has been advancing substantially, infertility treatment success rate increased over years. Many men and women with fertility problems have been treated successfully through well-known and reliable methods verified by infertility specialists.  Actually with current state of infertility treatment, there is absolutely no fertility problem that is not curable through existing methods. Iran is one of the pioneers in treating infertility for men and women. To lea more about these methods, some of main approaches to infertility treatment are explained below.

Common methods of infertility treatment:

Given the main cause of infertility, there are various options to treat fertility problems. Treatment usually begins with methods with lowest risk and in case of lack of progress, other methods would be applied.

• Medication:

In some cases, infertility is caused by disorderliness of hormonal balance or reduction of hormonal storage. In these situations, treatment would be sought through medication. Taking fertility medicines can effectively improve the function of reproductive organs in men and women. Even in some occasions that the cause of infertility is unknown, it is possible to achieve natural fertilization by taking medication.

• IUI:

Another treatment for infertility is intrauterine insemination IUI. This method involves placing sperm samples inside woman’s uterus helping sperm to reach fallopian tubes thus increasing the chance of fertilization. This method is applied when sperm is unable to reach to the eggs.

• Surgery

Another approach to infertility treatment is laparoscopy or other extensive abdominal operations. This approach is pursued when infertility is caused by blocked fallopian tubes or diseases such as uterine fibroids, ovarian cysts, endometriosis or anatomical problems in genitals.

• Assisted reproduction techniques:

In cases where infertility is caused by low sperm count or blocked fallopian tubes, the treatment is very exceptional. It’s called In Vitro Fertilization or IVF. IVF is used only when other treatments proved to be ineffective. In this method infertility specialist collects sperm and egg and unites them in a laboratory using advanced equipment, a process that naturally occurs inside fallopian tubes. IVF is one of the prevailing methods for infertility treatment and assisted reproduction techniques.

 

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IVF : history of IVF in Iran

The history of IVF in Iran has been shaped by the interaction between the pioneers of IVF and an interdisciplinary group of experts, together with the endorsement and strong support of the Shia jurists.

• 1992 Birth of the first baby following retrograde ejaculation using intrauterine insemination (IUI) first started in 1989 in Aban Hospital by Dr. Jalil Pakravesh (personal communication).
• 1994 Birth of the first baby resulting from intracytoplasmic sperm injection (ICSI) and the birth of the first baby through egg donation carried out in Yazd by Dr. Mohmmad-Hossein Amir Arjomand (personal communication).
• 1996/97 Use of ICSI + percutaneous epididymal sperm aspiration (PESA) resulting in the birth of a baby at Shariati Hospital, Tehran, carried out by Dr. Hojat-Allah Saeedi (personal communication).
• 1998 First case of transferring an embryo produced from testicular spermatozoon by microinjection carried out by Dr. Akhondi (the author).
• 2004 Birth of the first baby bo following pre-implantation genetic diagnosis (PGD) Royan Institute, Tehran, carried out by Dr. Leila Karimian (personal communication).

Indeed, the use of IVF in a range of contexts such as PGD(more…) (as a preventive measure for diseases with a genetic basis or for sex selection); sperm, egg and embryo donation; surrogacy; fertility preservation; and animal conservation (freezing of egg, sperm and embryo), are commonplace in Iran.

 

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IVF : Infertility treatment in Iran

According to the World Health Organization (WHO), infertility is a disease of the reproductive system defined by the failure to achieve a clinical pregnancy after 12 months of trying.

Infertility affects an estimated 20.4 % of couples globally.

The figure will drop to 12.4 percent after two years of trying, adding it shows that many infertile couples can have a baby if they keep trying.

The couples aged 35 years and above are not recommended to use the method because any delay in childbearing would aggravate their infertility problems(more…).

Iranian couples no longer need to travel abroad for consultation or treatment for infertility as advanced methods of treatment for couples who have problems to conceive, are available in the country.

There are 3 million infertile couples in the country.  Around 3-4% of young Iranian women suffer from recurrent miscarriages. Infertility rate is about 2.5% and secondary infertility is more prevalent than primary infertility. When a woman is not able to conceive at all, (due to infertility in either spouse), it is referred to as primary fertility. Secondary infertility is when a woman is unable to conceive again after the first successful pregnancy and childbirth. While causes of secondary infertility vary, the most important risk factors are advanced reproductive age, weight gain, abdominal surgeries, sperm quality and quantity, and smoking.

Microsurgical reconstruction for male infertility, new methods of male infertility treatment(more..) (medication, surgery, and Intracytoplasmic Sperm Injection (ICSI)(more…)), the role of complementary therapies and medicines to improve fertility, and new imaging techniques for assessment of infertility problems in both genders, are among the main important topics that will be discussed.

At present, there are 80 infertility centers across the country and 20 more will be launched by the end of the current year.

Additionally, 35 state-run universities of medical sciences have equipped with new laboratory equipment and devices for identification and treatment of infertility problems.

 

 

IVF is never the first step in the treatment of infertility. Instead, it’s reserved for cases in which other methods such as fertility drugs, surgery, and artificial insemination haven’t worked.

On average, an IVF cycle costs $2,300-$2,900 in the country, while the majority of women have per-cycle success rates of 20-35%, which means they may need multiple tries to get pregnant.

IVF may be an option if one of the spouses or both has been diagnosed with problems like endometriosis, low sperm count, problems with ovulation, antibody problems that harm sperms or eggs, and unexplained fertility problems.

 

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IVF: side effects

Typical side effects include:

• Passing a small amount of clear or bloody fluid shortly after the procedure — due to the swabbing of the cervix before the embryo transfer
• Breast tendeess due to high estrogen levels
• Mild bloating
• Mild cramping
• Constipation

If you develop moderate or severe pain after the embryo transfer, contact your doctor. He or she will evaluate you for complications such as infection, twisting of an ovary (ovarian torsion) and severe ovarian hyperstimulation syndrome.

About 12 days to two weeks after egg retrieval, your doctor will test a sample of your blood to detect whether you’re pregnant.

• If you’re pregnant, your doctor will refer you to an obstetrician or another pregnancy specialist for prenatal care.
• If you’re not pregnant, you’ll stop taking progesterone and likely get your period within a week. If you don’t get your period or you have unusual bleeding, contact your doctor. If you’re interested in attempting another cycle of in vitro fertilization (IVF), your doctor might suggest steps you can take to improve your chances of getting pregnant through IVF.

The chances of giving birth to a healthy baby after using IVF depend on various factors, including:

• Mateal age. The younger you are, the more likely you are to get pregnant and give birth to a healthy baby using your own eggs during IVF. Women age 41 and older are often counseled to consider using donor eggs during IVF to increase the chances of success.
• Embryo status. Transfer of embryos that are more developed is associated with higher pregnancy rates compared with less developed embryos (day two or three). However, not all embryos survive the development process. Talk with your doctor or another care provider about your specific situation.
• Reproductive history. Women who’ve previously given birth are more likely to be able to get pregnant using IVF than are women who’ve never given birth. Success rates are lower for women who’ve previously used IVF multiple times but didn’t get pregnant.
• Cause of infertility. Having a normal supply of eggs increases your chances of being able to get pregnant using IVF. Women who have severe endometriosis are less likely to be able to get pregnant using IVF than are women who have unexplained infertility(more…).
• Lifestyle factors. Women who smoke typically have fewer eggs retrieved during IVF and may miscarry more often. Smoking can lower a woman’s chance of success using IVF by 50 percent. Obesity can decrease your chances of getting pregnant and having a baby. Use of alcohol, recreational drugs, excessive caffeine, and certain medications also can be harmful.

IVF

When choosing an in vitro fertilization (IVF) clinic, keep in mind that a clinic’s success rate depends on many factors, such as patients’ ages and medical issues, as well as the clinic’s treatment population and treatment approaches. Ask for detailed information about the costs associated with each step of the procedure.

Before begiing a cycle of IVF using your own eggs and sperm, you and your partner will likely need various screenings, including:

• Ovarian reserve testing. To determine the quantity and quality of your eggs, your doctor might test the concentration of follicle-stimulating hormone (FSH), estradiol (estrogen) and antimullerian hormone in your blood during the first few days of your menstrual cycle. Test results often used together with an ultrasound of your ovaries, can help predict how your ovaries will respond to fertility medication.
• Semen analysis. If not done as part of your initial fertility evaluation, your doctor will conduct a semen analysis shortly before the start of an IVF treatment cycle.
• Infectious disease screening. You and your partner will both be screened for infectious diseases, including HIV.
• Practice (mock) embryo transfer. Your doctor might conduct a mock embryo transfer to determine the depth of your uterine cavity and the technique most likely to successfully place the embryos into your uterus.
• Uterine cavity exam. Your doctor will examine your uterine cavity before you start IVF. This might involve a sonohysterography — in which fluid is injected through the cervix into your uterus — and an ultrasound to create images of your uterine cavity. Or it might include a hysteroscopy — in which a thin, flexible, lighted telescope (hysteroscope) is inserted through your vagina and cervix into your uterus

 

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IVF

Specific steps of an in vitro fertilization (IVF) cycle carry risks, including:

• Multiple births. IVF increases the risk of multiple births if more than one embryo is implanted in your uterus. A pregnancy with multiple fetuses carries a higher risk of early labor and low birth weight than pregnancy with a single fetus does.
• Premature delivery and low birth weight. Research suggests that the use of IVF slightly increases the risk that a baby will be bo early or with low birth weight.
• Ovarian hyperstimulation syndrome. Use of injectable fertility drugs, such as human chorionic gonadotropin (HCG), to induce ovulation can cause ovarian hyperstimulation syndrome, in which your ovaries become swollen and painful. Signs and symptoms typically last a week and include mild abdominal pain, bloating, nausea, vomiting, and diarrhea. If you become pregnant, however, your symptoms might last several weeks. Rarely, it’s possible to develop a more severe form of ovarian hyperstimulation syndrome that can also cause rapid weight gain and shortness of breath.
• Miscarriage. The rate of miscarriage for women who conceive using IVF with fresh embryos is similar to that of women who conceive naturally — about 15 to 25 percent — but the rate increases with mateal age. Use of frozen embryos during IVF, however, may slightly increase the risk of miscarriage.
• Egg-retrieval procedure complications. Use of an aspirating needle to collect eggs could possibly cause bleeding, infection or damage to the bowel, bladder or a blood vessel. Risks are also associated with general anesthesia is used.
• Ectopic pregnancy. About 2 to 5 percent of women who use IVF will have an ectopic pregnancy — when the fertilized egg implants outside the uterus, usually in a fallopian tube. The fertilized egg can’t survive outside the uterus, and there’s no way to continue the pregnancy.

IVF

Why it’s done

Sometimes, IVF is offered as a primary treatment for infertility in women over age 40. IVF can also be done if you have certain health conditions. For example, IVF may be an option if you or your partner has:

• Fallopian tube damage or blockage. Fallopian tube damage or blockage makes it difficult for an egg to be fertilized or for an embryo to travel to the uterus.
• Ovulation disorders. If ovulation is infrequent or absent, fewer eggs are available for fertilization.
• Premature ovarian failure. Premature ovarian failure is the loss of normal ovarian function before age 40. If your ovaries fail, they don’t produce normal amounts of the hormone estrogen or have eggs to release regularly.
• Endometriosis. Endometriosis occurs when the uterine tissue implants and grows outside of the uterus — often affecting the function of the ovaries, uterus and fallopian tubes.
• Uterine fibroids. Fibroids are benign tumors in the wall of the uterus and are common in women in their 30s and 40s. Fibroids can interfere with implantation of the fertilized egg.

What is IVF or In Vitro Fertilization?

In vitro fertilization (IVF)(more…) is a process of fertilization where an egg is combined with sperm outside the body, in vitro (“in glass”). The process involves monitoring and stimulating a woman’s ovulatory process, removing an ovum or ova (egg or eggs) from the woman’s ovaries and letting sperm fertilize them in a liquid in a laboratory. After the fertilized egg (zygote) undergoes embryo culture for 2 6 days, it is implanted in the same or another woman’s uterus, with the intention of establishing a successful pregnancy.

Overview

IVF is the most effective form of assisted reproductive technology. The procedure can be done using your own eggs and your partner’s sperm. Or IVF may involve eggs, sperm or embryos from a known or anonymous donor. In some cases, a gestational carrier — a woman who has an embryo implanted in her uterus — might be used.

Your chances of having a healthy baby using IVF(more…) depend on many factors, such as your age and the cause of infertility(more…). In addition, IVF can be time-consuming, expensive and invasive. If more than one embryo is implanted in your uterus, IVF can result in a pregnancy with more than one fetus (multiple pregnancies).

 

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Rhinoplasty methods:

As mentioned above, nowadays rhinoplasty is being performed with various methods all around the world, here are these methods:

• Open procedure:

In this procedure rhinoplasty is applied to reshape the nose. This procedure can be used to change and resize different features of the nose such as span of the nostrils, angle between nose and upper lip, tip and/or bridg of the nose. It also can be applied to correct some breathing problems. People who has problem in Sinus or Polyp area, can be treated through rhinoplasty.

This procedure must be performed by doctors specialized in ear-throat-nose field (ENT) or plastic surgery or Maxillofacial surgery. Because only these specialist has the needed expertise to perform this surgical procedure. In this method, an incision is made across the narrow strip of tissue that separates the nostrils.

• Closed procedure:

Another method for rhinoplasty is the closed procedure. In this method the incisions are hidden inside a patient’s nose, with incision made into the nose. having access to the cartridge and bone portions of the nose, surgeon is able to perform changes that need to be made. This method is usually used to remove nose hump. It’s important to note that this procedure should only be performed on patients who aren’t dealing with polyp, sinus or any other breathing difficulties. Should patient sustained any injuries during this procedure, doctor will have to perform open rhinoplasty.

Open rhinoplasty and closed rhinoplasty surgery are different and each has its own traits, so it can’t be said for sure that one is superior to another. One of the advantages of open rhinoplasty is that it enables the surgeon to resolve nose problems easily and make various changes. But in case of closed rhinoplasty, surgeon can only remove nose hump and it might not eliminate the problem completely. Many doctors who perform rhinoplasty prefer the open procedure, unless patient is dealing with various health problems.Rhinoplasty In Iran , Rhinoplasty Cost In Iran ,Nose Job in Iran

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Why Rhinoplasty in Iran?

We have the best plastic surgeons in Iran who are highly efficient and have high experience in cosmetic surgery. We are therefore ready to meet all medical needs in Iran for foreign customers from all over the world with free medical consultation service. The rhinoplasty surgeons in Iran is characterized by having excellent experience and excellence in the field of surgery and beauty and the doctor and medical staff to give the patient the beautiful natural appearance

How much does a nose job cost in Iran?

The cost of doing nose job in Iran is divided into hospital expenses, surgeon expenses, and is variable based on the case, nasal specialist’s diagnosis and discussable.

The approximate price of a nose job in Iran is about 1000 to 5000 Euro.

Rhinoplasty Surgery:

Nowadays rhinoplasty aka nose job, is one of the surgical procedures that is widely used by many people around the world to reshape their nose. It’s worth to know that the nose is one of the most distinctive features of your face and its function is critical to your beauty. Many people use rhinoplasty because they aren’t satisfied with their nose’s appearance while others do it due to breathing difficulties. This surgical procedure is operated with different methods each having its own traits. Below we explain some of these methods.

 

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Rhinoplasty Follow-up

A brief summary of post-rhinoplasty recommendations given to patients is as follows:

• Prevent injury to your nose. Minimize all activities, and be very careful.
• Avoid blowing your nose. Wipe your nose gently with tissues. If you sneeze, try to keep your mouth open.
• Change the dressing (if you have one) under the nose as needed.
• Avoid extreme physical activity. Strive for more rest than usual, and avoid exertion.
• Brush your teeth gently with a soft toothbrush only.
• Avoid manipulating your upper lip, which helps keep your nose at rest.
• Avoid smiling or excessive facial movements for 1-2 weeks.
• Wear clothing that fastens in front or back for 1 week. Avoid slipover sweaters, tight tee shirts, and turtlenecks.
• Avoid foods that require prolonged chewing. This is the only dietary restriction related to the rhinoplasty.
• You may wash your face, but avoid getting the nasal cast wet.
• Do not wash your hair for 1 week, unless you have someone who can do it for you.
• Do not get your nasal dressing wet.
• Absolutely avoid taing for 6 weeks after surgery.
• Do not wear regular glasses or sunglasses that rest on the bridge of the nose for at least 4 weeks. You may tape the glasses to your forehead.

 

Rhinoplasty in iran :

Rhinoplasty describes an array of operative techniques that can be used to alter the aesthetic and functional properties of the nose.  Surgical access to the nose can be gained via incisions placed inside the nose (endonasal approaches) or via incisions placed inside the nose combined with incisions placed outside the nostrils (exteal approach), usually on the columella. Prior to the increased popularity of the exteal (open) rhinoplasty approach in the last decade, the terms rhinoplasty and endonasal rhinoplasty were almost synonymous. This somewhat artificial division between exteal (open) and endonasal (closed) rhinoplasty has become an established part of current rhinoplasty nomenclature. Despite this, both approaches share many of the same incisions, and many of the same principles apply regardless of the approach chosen.